Glycated haemoglobin and serum fructosamine concentrations in sick, non-diabetic dogs receiving oral prednisolone.

Oral prednisolone increases HbA1c and fructosamine in non-diabetic dogs.

This study investigated the effects of oral prednisolone on glycated hemoglobin (HbA1c) and serum fructosamine concentrations in non-diabetic dogs. Glucocorticoids like prednisolone are known to increase the risk of developing diabetes mellitus in dogs, but their impact on these specific biomarkers had not been extensively studied. The research aimed to fill this gap by evaluating HbA1c and fructosamine levels in non-diabetic dogs undergoing oral prednisolone therapy. The findings revealed that treatment with oral prednisolone led to significant increases in both HbA1c and serum fructosamine concentrations. These results suggest that monitoring these biomarkers could be valuable in assessing the metabolic effects of glucocorticoid therapy in dogs. Veterinary professionals should be aware of the potential for glucocorticoids to alter these markers, which may influence the interpretation of diagnostic tests and the management of canine patients receiving such treatments.

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