Swollen paw pads in a 10-year-old castrated male domestic shorthair cat.
Fultz RJ, Frank CB · Journal of the American Veterinary Medical Association · 18 February 2026
Swollen paw pads in cats require systematic diagnostic evaluation including histopathology.
This case report describes the clinical presentation and diagnostic approach to swollen paw pads in a 10-year-old castrated male domestic shorthair cat. Swollen paw pads, or pillow foot/plasma cell pododermatitis, represents an important differential diagnosis in feline patients presenting with digital swelling and lameness. The condition can result from various etiologies including infectious, inflammatory, neoplastic, or idiopathic causes. The authors discuss the clinical examination findings, diagnostic imaging considerations, and potential treatment modalities for this presentation. Histopathological examination often plays a crucial role in establishing a definitive diagnosis, particularly when differentiating between benign and neoplastic conditions. The case highlights the importance of thorough physical examination, appropriate diagnostic imaging, and tissue sampling in geriatric feline patients presenting with localized swelling. Management depends on the underlying etiology and may include medical therapy, surgical intervention, or palliative care. This case contributes to the veterinary literature by illustrating the diagnostic challenges and clinical considerations when evaluating swollen paw pads in domestic cats, particularly in older animals where multiple disease processes may be concurrent.
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