Acute kidney injury is associated with increased mortality in dogs with gastric dilatation and volvulus.
Suarez-Rodriguez JI, Lourenço BN, Huang JHC, Brainard BM, Schmiedt CW · Journal of the American Veterinary Medical Association · 25 February 2026
AKI in GDV dogs significantly increases mortality risk; assess kidney function perioperatively.
This retrospective study examined 106 dogs undergoing surgical correction for gastric dilatation and volvulus (GDV) between 2013-2023, evaluating the prevalence and impact of acute kidney injury (AKI). AKI occurred in 18.9% of cases, with 17.0% presenting with AKI at admission. Dogs with AKI had significantly higher mortality rates, with those presenting with AKI showing 7.90 times greater odds of death, and those developing AKI at any point showing 9.23 times greater odds. Preoperative lactate levels were independently associated with presenting AKI, while multivariate analysis identified intraoperative hypotension, hetastarch administration, and AKI as significant mortality predictors. The findings emphasize that concurrent AKI is common in GDV cases and substantially increases mortality risk. The authors recommend careful perioperative assessment of kidney function and consideration of fluid management strategies, particularly regarding colloid use, to optimize outcomes in GDV patients.
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