Evaluation of safety and efficacy of an ophytrium and seboliance-containing mousse with or without shampoo in cats with keratinisation disorders.
Noli C, Dropsy H, Cozar A, De Jaeger X, Kesteman R, Beck A, Cristante R, Debraine M, Leymarios F, Puozzo-Barichard A, Gatellet M · Journal of Small Animal Practice · 26 February 2026
Ophytrium-containing topical protocol effectively reduces seborrhoea in cats with keratinisation disorders.
This prospective clinical study evaluated the safety and efficacy of an ophytrium and seboliance-containing topical protocol (DOUXO® S3 SEB Shampoo and Mousse) in 19 client-owned cats with keratinisation disorders presenting with seborrhoea. Nineteen cats were treated with either shampoo or mousse at baseline, followed by mousse application every 48-72 hours for 3 weeks. Clinical assessment using a modified Skin Seborrheic Index occurred at days 0, 7, and 21, measuring affected body surface area, scaling, coat greasiness, and secondary signs. Of 17 completing cats, SSI scores improved significantly by day 7 and 21, with ≥50% reduction in 82.4% of cases. By day 21, affected body surface decreased 92.9%, scaling 70.5%, and greasiness 68.3%. Veterinarians rated improvement as satisfactory to excellent in 100% of cases. Owners reported 100% effectiveness and 88.2% practicality ratings, with 94.1% observing improved skin and coat condition. The protocol demonstrated excellent tolerability with no reported adverse effects, establishing it as an effective and practical therapeutic option for feline seborrhoea.
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