Feline Panleukopenia: Analysis of Possible Survival Biomarkers.

Single admission hematologic indexes poorly predict FPV survival in cats; longitudinal monitoring needed.

This study evaluated potential prognostic biomarkers for feline panleukopenia virus (FPV) infection in 58 cats admitted to a university teaching hospital between 2017-2025. Researchers analyzed demographic variables (age, sex) and hematological/biochemical parameters (hematocrit, leukocyte counts, neutrophils, lymphocytes, platelets, neutrophil:lymphocyte ratio [NLR], platelet:lymphocyte ratio [PLR], albumin, and potassium) collected at hospital admission. The case fatality rate was 10.3% (6/58 cats). Despite non-survivors showing trends toward lower hematocrit, albumin, and neutrophil values with relative lymphocytosis, no statistically significant differences were identified for any analyzed variables. The authors concluded that hematologic indexes such as NLR and PLR have limited prognostic utility in cats with FPV. They recommend larger prospective studies with dynamic biomarker monitoring during hospitalization and incorporation of complementary parameters for improved prognostic stratification and survival prediction in feline panleukopenia cases.

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