Lignocaine and phenylephrine spray prior to brachycephalic obstructive airway syndrome surgery in dogs reduces postoperative regurgitation: a prospective, randomized, controlled trial.

Lignocaine-phenylephrine spray reduces postoperative regurgitation in brachycephalic dogs undergoing BOAS surgery.

This prospective, randomized, controlled trial evaluated the efficacy of intraoral lignocaine and phenylephrine spray in 98 brachycephalic dogs undergoing elective corrective airway surgery. Dogs were randomized to receive either 10 actuations of lignocaine-phenylephrine spray or placebo prior to surgery. Standardized anesthetic protocols were implemented for all subjects, with outcome measures including intraoperative and postoperative opioid requirements, respiratory complications, and gastrointestinal complications assessed between groups. While intraoperative and postoperative methadone requirements did not differ significantly between treatment and control groups, postoperative regurgitation occurred significantly more frequently in the placebo group (odds ratio 8.1, 95% CI 2.5-37.0). No differences were observed in postoperative respiratory complications between groups. These findings suggest that locoregional vasoconstrictive anesthesia techniques via intraoral lignocaine-phenylephrine spray effectively reduce postoperative gastrointestinal complications in brachycephalic dogs undergoing BOAS corrective surgery, warranting consideration as part of multimodal anesthesia protocols for this surgical population.

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