Evaluation of high flow oxygen therapy in healthy neonatal bull calves.

HFOT is well-tolerated in neonatal calves and improves oxygenation across all flow rates tested.

This randomized crossover study evaluated high flow oxygen therapy (HFOT) in 10 healthy neonatal bull calves ≤10 days of age using two devices (Airvo 3 and Volumax) at three flow rates (0.2, 0.4, 1.0 L/kg/min). HFOT delivers warm, humidified oxygen with positive inspiratory and end-expiratory pressures, well-established in dogs and humans but previously unevaluated in cattle. The study measured physiological parameters including heart rate, respiratory rate, temperature, arterial blood gases, nasopharyngeal pressure, and end-tidal CO2 before and after 10-minute equilibration periods. Results demonstrated that HFOT was well-tolerated with no significant changes in heart rate, respiratory rate, temperature, or end-tidal CO2 across any flow rate. Importantly, oxygenation (PaO2) and nasopharyngeal pressure increased significantly with increasing flow rates on both devices. The Airvo 3 showed increased PaCO2 with higher flow rates, while the Volumax did not. These findings establish HFOT as a viable, safe alternative oxygen delivery method in neonatal cattle, potentially offering advantages over traditional nasal cannulas.

This summary was distilled by AI and may occasionally misinterpret data. Confirm critical details with the primary literature before clinical application.