Poorly differentiated sarcoma involving the mitral valve in a golden retriever.

Intracardiac sarcoma caused LVOT obstruction and rapid clinical deterioration in a Golden Retriever.

This case report describes a six-year-old neutered male Golden Retriever presenting with exercise intolerance, syncope, and a newly detected heart murmur. Echocardiographic evaluation revealed a large intracardiac mass within the left ventricle causing severe left ventricular outflow tract (LVOT) obstruction. The dog's condition deteriorated rapidly, and the patient was euthanized following acute respiratory distress. Necropsy findings demonstrated a substantial multilobular mass extending along the mitral valve base with firm adhesion to the left ventricular endocardium. Histopathological examination combined with immunohistochemical staining confirmed the diagnosis of poorly differentiated sarcoma. This case highlights the importance of echocardiography in diagnosing intracardiac masses and demonstrates that cardiac sarcomas, while rare, should be considered in the differential diagnosis for dogs presenting with acute cardiac dysfunction and LVOT obstruction. The rapid clinical deterioration and the infiltrative nature of the tumor emphasize the grave prognosis associated with intracardiac malignancies in veterinary patients.

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