Methemoglobinemia Secondary to Zinc Foreign Body Ingestion in a Dog.

Methemoglobinemia may occur with zinc toxicosis and should be evaluated.

This case report describes a novel presentation of methemoglobinemia in a dog with zinc toxicosis secondary to foreign body ingestion. Zinc toxicosis in canines typically manifests with gastrointestinal dysfunction, pancreatitis, hemolytic anemia, and acute kidney injury. The presented case is notable for the concurrent development of mild methemoglobinemia, which has not been previously documented in association with zinc intoxication in dogs. The dog developed progressive multi-organ dysfunction leading to cardiopulmonary arrest. The authors emphasize that methemoglobinemia may contribute to tissue hypoxia in zinc-intoxicated patients and suggest that evaluation for this condition should be considered in dogs with zinc toxicosis. The case highlights an important but understudied complication of zinc exposure that warrants further investigation to determine its clinical significance and impact on patient outcomes.

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