Performing liver biopsies in cattle.
Gibbons P, Roof C, Brooks W · Journal of the American Veterinary Medical Association · 8 April 2026
Liver biopsy is essential for cattle herd health diagnosis and mineral assessment.
This instructional resource describes the procedural steps for performing standing percutaneous liver biopsies in cattle, applicable to both beef and dairy operations. The article outlines the complete process including patient positioning, ultrasound-guided localization (particularly in dairy cows), use of manual biopsy instrumentation, and proper sample collection and handling techniques. Liver biopsy serves dual diagnostic purposes in cattle: histopathological examination for disease assessment and mineral analysis for nutritional and metabolic evaluation. Despite being a valuable herd health management tool, liver biopsy techniques are uncommonly taught in veterinary curricula. This procedural guide addresses that educational gap by demonstrating the technical aspects necessary for successful sample acquisition. The standing approach offers practical advantages for field application in production animal settings. Proper sample handling is emphasized as critical for maintaining diagnostic quality. The technique's utility in identifying hepatic pathology and assessing mineral status makes it particularly relevant for dairy herd health programs and beef cattle management.
This summary was distilled by AI and may occasionally misinterpret data. Confirm critical details with the primary literature before clinical application.