Intraoperative use of N-butyl cyanoacrylate for haemostasis following cavotomy for tumour thrombus removal in dogs undergoing adrenalectomy.

N-butyl cyanoacrylate is safe and effective for hemostasis after CVC venotomy closure in dogs.

This retrospective case series describes the novel application of N-butyl cyanoacrylate (surgical glue) as an adjunctive hemostatic technique following caudal vena cava (CVC) venotomy closure during adrenalectomy in five dogs with vascular invasion. The study reviewed medical records from January 2022 to August 2025 at a single referral center. Of 25 dogs undergoing cavotomy for adrenal tumors, five met inclusion criteria (3 pheochromocytomas, 2 adrenocortical carcinomas). N-butyl cyanoacrylate was applied post-suturing to control minor suture-line bleeding, applied either at suture entry points (3 dogs) or along the suture line (2 dogs). No intraoperative complications were associated with the adhesive application. Postoperatively, two dogs experienced minor complications (self-limiting hypertension and thrombophlebitis). Critical findings included absence of thrombosis or CVC obstruction during follow-up. Three dogs survived to final follow-up; two died of unrelated causes. The results suggest N-butyl cyanoacrylate is a safe and effective adjunctive hemostatic method for controlling minor bleeding during CVC closure in dogs undergoing complex adrenal surgery with vascular involvement.

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