EXPRESS: Ultrasonographic findings of feline large intestinal adenocarcinoma and high-grade lymphoma.
Khodari JA, Penninck D, Anson A · Journal of Feline Medicine and Surgery · 28 May 2026
Ultrasound aids differentiation but cytology/histology essential for definitive feline intestinal neoplasia diagnosis.
This retrospective study analyzed ultrasonographic findings in 82 cats with large intestinal neoplasia: 44 with adenocarcinoma (ACA) and 38 with high-grade lymphoma (LSA). ACA primarily affected the colon (28/44) and ileocolic junction (16/44) with median tumor length of 22.85mm and wall thickening of 9mm. Regional lymphadenopathy was present in 29/44 cats. Obstruction occurred in 30% of ACA cases. LSA predominantly involved the ileocolic junction (20/38) and colon (14/38) with median length of 48mm and wall thickening of 15mm; 31/38 cats had lymphadenopathy (median 11mm) and 7/38 had extraintestinal involvement. Obstruction was less common in LSA (11%). Both neoplasias presented as transmural, hypoechoic wall thickening with loss of layering. LSA lesions were significantly thicker, longer, and associated with more pronounced lymphadenopathy compared to ACA. ACA more frequently caused obstruction, while LSA showed multicentric distribution. Median survival was 19 days (ACA) and 23 days (LSA). Overlapping ultrasonographic features necessitate cytologic or histologic sampling for definitive diagnosis.
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