Preliminary investigation of T-wave peak-end interval and its ratio to QT interval in dogs with an echocardiographic phenotype of dilated cardiomyopathy and its possible correlation with left ventricular diameter and volume.

TpTe:QT ratio correlates with left ventricular remodeling in canine DCM independent of heart rate.

This cross-sectional study investigated T-wave peak-end (TpTe) interval and its ratio to QT interval (TpTe:QT) as electrocardiographic markers of myocardial repolarization dispersion in dogs with dilated cardiomyopathy (DCM). Researchers analyzed ECGs and echocardiographic data from dogs with DCM phenotype (excluding sighthounds) collected between July 2021 and June 2023, excluding those on antiarrhythmic medications. Results demonstrated that TpTe:QT showed significant weak-to-moderate correlations with left ventricular structural parameters including normalized end-diastolic and end-systolic diameters and volumes, even after heart rate adjustment. Notably, TpTe:QT exhibited negligible correlation with heart rate itself. Conversely, traditional QT and corrected QT intervals showed no significant associations with echocardiographic variables. These findings suggest TpTe interval and TpTe:QT ratio represent heart rate-independent ECG markers that may reflect myocardial structural remodeling in canine DCM, potentially offering additional diagnostic utility beyond conventional repolarization parameters.

This summary was distilled by AI and may occasionally misinterpret data. Confirm critical details with the primary literature before clinical application.