Therapeutic Outcomes and Owner Assessment in Canine Sebaceous Adenitis Across Breeds: A Multicentre Retrospective Analysis and Owner Survey.

Sebaceous adenitis management requires individualized approaches; breed and treatment modality alone cannot predict outcomes.

This multicentre retrospective study evaluated therapeutic outcomes in 122 dogs with sebaceous adenitis (SA) over a 10-year period, supplemented by an owner survey (35 respondents). Response to therapy was assessed using medication score reduction and flare frequency post-maintenance. Results showed excellent response in 18.9% of cases, good in 29.5%, fair in 21.3%, no improvement in 10.7%, and progressive disease in 18.9%. Notably, medication score improvements did not differ significantly by breed (p=0.114), and multimodal therapy achieved maintenance fastest. Post-maintenance flare occurrence was documented in 39% of dogs. A significant discordance was observed between owner perceptions and objective clinical response categories. The authors conclude that SA therapeutic outcomes cannot be reliably predicted based on breed or specific treatment modality, emphasizing the necessity for individualized case management with medication adjustments based on patient-specific treatment response rather than breed-based or protocol-driven approaches.

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