Clinical Efficacy of Probiotic-Based Ear Drops Containing Lactobacilli in Canine Erythroceruminous Otitis Externa: An Open Label, Multicentre Study.

Probiotic ear drops effectively reduce clinical signs in canine non-infectious otitis externa.

This open-label, multicentre study evaluated probiotic-based ear drops containing Lactobacilli in 37 dogs with non-infected erythroceruminous otitis externa (OE). Dogs received topical probiotic drops every 48 hours for 28 days. Clinical assessments at enrollment, day 14, and day 28 included cytological evaluation, pruritus scoring (PVAS), lesion severity (OTIS3), and quality-of-life surveys. Significant improvements were documented, with mean OTIS3 scores decreasing from 5.11±1.20 to 1.66±1.75 and PVAS scores declining from 4.93±1.51 to 2.09±2.03 by day 28. Clinical improvement occurred irrespective of concurrent medication use or initial microorganism overgrowth patterns. Owner-reported quality of life improved in 80% of cases. The findings support probiotics as adjunctive therapy for non-infectious canine otitis externa, potentially addressing the underlying microbiota dysbiosis associated with allergic conditions. Further controlled trials are warranted to establish optimal dosing and compare efficacy against standard treatments.

This summary was distilled by AI and may occasionally misinterpret data. Confirm critical details with the primary literature before clinical application.