EXPRESS: SURGICAL REPAIR OF STEROIDAL AND NONSTEROIDAL ANTI-INFLAMMATORY DRUG-ASSOCIATED FULL THICKNESS GASTROINTESTINAL ULCERS IN 10 CATS.

Surgical repair of drug-induced GI perforations in cats carries favorable prognosis with good survival rates.

This retrospective study analyzed 10 cats that underwent surgical repair for gastrointestinal ulcer perforation associated with NSAID and/or corticosteroid administration across five UK referral hospitals between 2009-2024. The proximal duodenum was the most common perforation site (60%), followed by the gastric body (20%). Surgical approaches varied, including primary repair (50%), Y-U pyloroplasty (20%), enterectomy (20%), and partial gastrectomy (10%). All cats survived the immediate postoperative period, with one death occurring 9 days postoperatively due to sepsis. Median hospitalization was 6 days. Long-term follow-up (median 928 days) showed 50% survival at study completion, with two deaths attributed to GI ulcer-related complications. Three cats experienced short-term complications, and one developed severe ulcerative duodenopathy. The study demonstrates that despite the high-risk nature of GI perforation, surgical correction in cats provides favorable outcomes, with the majority surviving to discharge and reasonable long-term survival rates.

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