Validation of Recalibrated IOPVet in Canine Eyes Compared to Manometry and Recalibrated TONOVET Plus.

Recalibrated IOPVet shows excellent sensitivity and acceptable specificity for detecting elevated canine IOP.

This validation study evaluated the clinical accuracy of a recalibrated IOPVet indentation tonometer in 97 canine eyes (49 dogs) compared to recalibrated TonoVet Plus (rTVP) and post-mortem manometry. The study included three groups: glaucomatous dogs (67 eyes), healthy controls (20 eyes), and euthanized dogs for manometric validation (10 eyes). IOPVet readings were recorded as semi-quantitative intervals (<10, 10-29, 30-49, ≥50 mmHg). Results demonstrated 100% sensitivity for detecting elevated IOP (≥30 mmHg) and 84.8% specificity for normotensive eyes, with 21.7% of normal eyes overestimated. Chi-square analysis confirmed significant agreement with rTVP (χ=50.2, p<0.0001). Manometric validation showed excellent accuracy: 95% (10-29 mmHg), 100% (30-49 mmHg), and 94% (≥50 mmHg), with no misclassifications below 30 mmHg. The recalibrated IOPVet demonstrates markedly improved diagnostic performance, making it suitable for clinical integration and owner-assisted glaucoma monitoring in veterinary practice.

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