Bilateral Eyelid Agenesis With Multiple Congenital Ocular Anomalies in an Australian Labradoodle Puppy: Case Report and Surgical Management.

Bilateral eyelid agenesis frequently associates with severe internal ocular malformations requiring enucleation.

A 15-week-old Australian Labradoodle puppy presented with bilateral lower eyelid agenesis/coloboma and multiple congenital ocular anomalies. Surgical management included enucleation of the left globe and lip-to-lid transmucosal flap repair of the right eyelid. Two months later, the right globe was enucleated due to prolapse of the nictitating membrane gland and absence of vision. Histopathological examination of both globes revealed bilateral Peters' anomaly (anterior chamber cleavage syndrome), characterized by Descemet's membrane defects, anterior synechiae, and drainage angle closure. Additional findings included persistent pupillary membranes, retinal separation, and aphakia. Histology of the right eyelid skin confirmed complete absence of conjunctival goblet cells, tarsal plate, and meibomian glands. This case represents an uncommon presentation of bilateral canine lower eyelid agenesis concurrent with multiple severe congenital ocular malformations, highlighting the complexity of managing syndromic ocular developmental disorders in dogs.

This summary was distilled by AI and may occasionally misinterpret data. Confirm critical details with the primary literature before clinical application.