EXPRESS: Treatment rationales and outcomes for cats with lens luxation: 136 eyes (2007-2023).

ICLE superior to medical management for lens luxation, but medical management acceptable when surgery unavailable.

This retrospective study evaluated treatment outcomes for feline lens luxation across 136 eyes from 115 cats over a 16-year period. Medical management was the most common initial approach (58% of eyes), followed by enucleation (24%), intracapsular lens extraction/ICLE (9%), and transcorneal lens reduction/TCLR (5%). Male cats were significantly overrepresented (77%). Key findings revealed that TCLR was unsuccessful in all treated eyes, making it non-viable for feline patients. ICLE proved most effective, with 92% of treated eyes achieving visual and normotensive status (IOP <25 mmHg). Medical management showed more modest results, with 38% achieving visual and normotensive status, though 66% remained normotensive and 74% of initially visual eyes retained vision. Treatment selection involved multiple factors: visual status (40%), perceived comfort (36%), age/medical history (29%), financial constraints (12%), medication compliance issues (10%), concurrent ocular findings (9%), and concerns about post-traumatic ocular sarcoma risk (7%). The authors emphasize that when ICLE is contraindicated, medical management can provide acceptable IOP control and vision preservation outcomes.

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